• 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro- 1,4-endo,endo-5,8-dimethanonaphthalene
Formula C12H8Cl6O
Description Endrin is a white crystalline, odorless solid dissolved in a liquid carrier.
Uses Formerly as insecticide.

Registry Numbers and Inventories.
CAS 72-20-8
EC (EINECS/ELINCS) 200-775-7
EC Index Number 602-051-00-X
EC Class Very toxic; Toxic; Dangerous for the Environment
RTECS IO1575000
RTECS class Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data
UN (DOT) 2761
Merck 12,3618
Beilstein/Gmelin 91397
Beilstein Reference 4-17-00-00525
EPA OPP 41601
Swiss Giftliste 1 G-1613
US TSCA Listed
Austrailia AICS Listed
Japan ENCS (MITI) Listed

Odor Threshold Odor threshold 118 ppb
Formula C12H8Cl6O
Formula mass 380.91
Melting point, C 240
Boiling point, C 416
Vapor pressure, mmHg 1E-6 (25 C)
Density 1.7 g/cm3 (20 C)
Solubility in water Insoluble
Partition coefficient, pKow 5.20
Heat of vaporization 64.3 kJ/mol

Hazards and Protection.
Storage Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection Protective gloves and clothing. Face shield or eye protection in combination with breathing protection if in powder form.
Respirators Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash or cement powder. Water spill: If dissolved, in region of 10 ppm or greater concentration, apply activated carbon at ten times the spilled amount. Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.
Stability Stable.
Incompatibilities Endrin has reacted violently with parathion. Avoid contact with strong oxidizers, strong acids, parathion.
Decomposition Decomposes above 200 C.

Flash Point,C 155
Fire fighting Use water to keep fire-exposed containers cool. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site. Move container from fire area if you can do it without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.Use dry chemical, foam, carbon dioxide, water spray for solution. Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam.
Fire potential Slight; dry powder is not flammable, but commercial solutions contain flammable liquids whose flashpoints may be as low as 80F.
Hazards Toxic hydrogen chloride and phosgene may be generated when solution burns. Avoid strong oxidizers, strong acids and parathion.
Combustion products Toxic hydrogen chloride and phosgene may be generated when solution burns.
NFPA Health 2
  Flammability 0  
  Reactivity 0  

Exposure limit(s) NIOSH REL: TWA 0.1 mg/m3 [skin] OSHA PEL: TWA 0.1 mg/m3 [skin] IDLH 2 mg/m3
Poison_Class 1
Exposure effects Respiratory depression, elevated body temperature, and recurrent abnormally low blood pressure have occurred in acute endrin poisoning. Sensory disturbances, excitation with myoclonic jerking, convulsions, tremor, ataxia, agitation, nervousness, and amnesia may occur. Permanent damage may occur following acute exposure. Endrin has been fetotoxic and embryotoxic in several species of experimental animals; other studies have not found teratogenic effects. Endrin is less likely to be transferred to breast milk than other organochlorine insecticides because it is metabolized relatively rapidly. Endrin has altered spermatogenesis in rats.
   Ingestion Nausea, vomiting, and diarrhea may occur following ingestion.
   Inhalation Reduced gas exchange, irritation, and chemical pneumonitis may occur.
   Skin Extensive contact results in dermal irritation.
   Eyes Hypersalivation and deafness may occur. White, foamy froth may emanate from the nose and mouth. Headache may persist for two to four weeks.

First aid
   Ingestion Seek medical assistance.
   Inhalation Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin Remove and isolate contaminated clothing and shoes. Remove material from skin immediately. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
   Eyes Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

UN number 2761
Response guide 151
Hazard class 6.1
Packing Group I; II; III  
Std. Transport # 4921521